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Amaranth...
is probably one of our oldest crops. Domesticated in Central America many
years B.C., it reached its zenith during the Aztec civilization. The
Emperor Montezuma filled his granaries with tons of amaranth for a period
of 5 to 10 years in order to withstand the ravages of drought, famine and
pestilence. An entirely edible plant, amaranth is grown in India, Mexico,
Guatemala, Peru, Russia, and in twenty-one states within the U.S.
The vitamin
E in amaranth is the rare form called tocotrienols, which is known
to regulate the enzyme that controls cholesterol biosynthesis.
Tocotrienol
may be 40 to 6000 times stronger as an antioxidant than Vitamin E,
depending upon the tocopherol fraction. Since it is oxidized cholesterol
that causes atherosclerosis this is a considerable advantage.
Tocotrienol,
at 200 mg, reduces cholesterol as much as 30% in one month in some
subjects, prevents LDL oxidation and inhibits atherosclerotic plaque. One
method of its action is accelerated degradation of the HMG-CoA reductase
enzyme, a different mechanism than the "statin" drugs (e.g.
Mevacor) which also affect this enzyme. HMG-CoA is the enzyme that creates
cholesterol. The anticholesterol effects of Tocotrienol work in about 75%
of those who take it. Those who do not respond have errors in cholesterol
transport or degradation.
People
have recently been advised to take an aspirin daily or every other day
to reduce platelet aggregation and the chances of a blood clot. Aspirin is
an irritant to the lining of the stomach and intestines, and may
contribute to leaky gut syndrome. Aspirin works by inhibiting thromboxane
A2. Tocotrienol
may be even more effective but without side effects.
Thromboxane B2 (the metabolite) is reduced by 31% and platelet aggregation
is decreased by 15% to 30%.
In animal
studies, subjects given Tocotrienol exhibited remarkable resistance to
acquiring liver or breast cancer. Subjects given chemicals to induce
cancer resisted it. Tocotrienol, in another study, inhibited melanoma and
breast cancer cells up to 50%.
A major
part of Tocotrienol (52%) is gamma tocopherol. This nutrient inhibits the
perioxynitrate radical, which especially attacks brain tissue. (Melatonin
does the same thing.) Reports have been especially critical of taking pure
alpha-tocopherol, as typically found in multivitamins, since without the
gamma fraction it may do more harm than good.
Tocotrienol
is also anti-inflammatory.
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